The Andrzej Soltan Institute for Nuclear Studies comprises 8 Research Departments, Training and Consulting Department, the ZdAJ production unit (manufacturer of medical accelerators) and several support units.

The following Departments are localized in Świerk:
P-II Department of Interdisciplinary Physics Applications
P-III Department of Nuclear Radiation Detectors and Electronics
P-V Department of Plasma Physics and Material Engineering
P-X Department of Particle Acceleration Physics and Technology
Laboratory of Astrophysical Instrumentation
Department of Training and Consulting
ZdAJ Production Unit

The following Departments are localized in Warsaw:
P-I Department of Nuclear Reactions
P-VI High Energy Physics Department
P-VIII Theoretical Physics Department

Single Department is localized in Łódź:
P-VII Department of Cosmic Ray Physics